SCIENCE

You have made the difficult first step towards cutting out alcohol from your life. The science of alcohol dependence and its impact on the body is vitally important to managing withdrawal and maintaining a healthier body. Everyone does it for different reasons, and it a difficult decision. It comes with challenges in many ways. One being the ability for your brain to manage and process the change when you go from drinking alcohol to excess to quitting alcohol. This can have negative side effects and leave you tired, irritable, forgetful, suffering from sleep deprivation, mood swings and brain fog. Desistal contains 2 potent nootropics that work to increase your NAD+ (Nicotinamide Adenine Dinucleotide is the main metabolite required for cell function which is negatively affected by alcohol). This powerful combination helps support brain function, maintain balance and reduce the negative side effects associated with post alcohol withdrawal syndrome.

Alcohol doesn’t calm you – it disrupts your brain’s natural balance

At first, you feel settled – your thoughts slow, your body unwinds. But behind that calm, your brain is scrambling to restore stability, dialling down its own ability to self-soothe. That’s why the “relaxation” fades fast and tension rebounds even harder later. This is what happens when you drink alcohol 1: Alcohol acts as a central nervous system depressant that disrupts brain balance by boosting GABA (calming neurotransmitter) and reducing glutamate (alertness chemical), creating temporary relaxation. 2: The brain compensates by reversing these levels, resulting in increased anxiety and stress once the alcohol wears off. 3: Alcohol mimics the calming chemical GABA, giving a temporary sense of relief, but the brain compensates by decreasing GABA production, leading to rebound anxiety or “hangxiety”. 4: While you might feel calm initially, the brain triggers a surge in glutamate (the “wired” chemical) afterwards, which creates heightened anxiety, racing thoughts, and sleep disruption. 5: Regular alcohol consumption causes the brain to adapt by reducing its natural ability to regulate stress, creating a reliance on alcohol to feel calm.
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The key ingredients in Desistal are:

Bacopa Monnieri

Typically used as a memory aid, Bacopa Monnieri helps to reduce the negative symptoms associated with quitting alcohol by supporting the brain function, reducing stress levels and enhancing mood and temperament.

Studies suggest that Bacopa monnieri acts as a natural nootropic and adaptogen that increases GABA (gamma-aminobutyric acid) levels in the brain, promoting relaxation, reducing anxiety, and enhancing stress resilience. It works by modulating GABAergic activity and upregulating GABA receptors, thereby helping balance neuronal excitation and providing a calming effect. These effects can be extremely beneficial when trying to curb cravings for alcohol. Learn more…

Acetate (Apple Cider Vinegar)

ACV provides a natural source of acetate to provide energy to the brain without alcohol. It can aid healthy digestion, support overall mental wellbeing via serotonin which stabilizes our mood, sleep cycle, positive mental attitude and sense of happiness

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MCT Oil Powder

MCT (Medium Chain Triglycerides) is a unique type of fat, that is transported straight to the liver where it is metabolized to produce ketones, known to raise the NAD+/NADH Ratio in the brain. This counterbalances the negative effects of withdrawal by acting as a replacement for the alcohol your brain has been using for energy and helps restore balance to your mind and body.

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